Name | GNE-6640 |
Synonyms | GNE6640 CS-2824 GNE 6640 GNE-6640 GNE-6641 2009273-67-8 Phenol, 4-[2-amino-4-ethyl-5-(1H-indazol-5-yl)-3-pyridinyl]- |
CAS | 2009273-67-8 |
Molecular Formula | C20H18N4O |
Molar Mass | 330.38 |
Density | 1.308±0.06 g/cm3(Predicted) |
Boling Point | 595.5±50.0 °C(Predicted) |
pKa | 8.23±0.15(Predicted) |
Storage Condition | -20℃ |
Use | GNE-6640 is a selective, non-covalent binding inhibitor of ubiquitin-specific peptidase 7 (USP7). Its IC50 values for the full length of USP7, the catalytic domain of USP7, the full length of USP43 and the Ub-MDM2 are 0.75 μM,0.43 μM,20.3 μM and 0.23 μM respectively. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.027 ml | 15.134 ml | 30.268 ml |
5 mM | 0.605 ml | 3.027 ml | 6.054 ml |
10 mM | 0.303 ml | 1.513 ml | 3.027 ml |
5 mM | 0.061 ml | 0.303 ml | 0.605 ml |